Basic and practical aspects of recombinant allergens
نویسندگان
چکیده
منابع مشابه
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15 صفحه اولHigh-throughput isolation of recombinant antibodies against recombinant allergens.
BENCHMARKS Immunoglobulin E (IgE)-mediated allergic diseases have become a serious health problem in industrialized countries (1,2). Routine diagnosis of allergic conditions is based on clinical history, skin test reactivity, and serum IgE determinations against the offending agents (3). Both skin test reactivity and determinations of serum IgE levels reflect directly on the quality of the al-l...
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Recombinant DNA technology is a common procedure to produce allergenic proteins in vitro. To date, more than 40 food allergens from fruits, vegetables, nuts, milk and seafood have been expressed as recombinant proteins. Since recombinant proteins can be produced in large quantities and in controlled quality, they promise to be suitable tools for precise diagnostics and research applications. "H...
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PURPOSE OF REVIEW Molecular allergology uses pure, mainly recombinant and structurally defined allergen molecules and allergen-derived epitopes to study mechanisms of IgE-associated allergy, to diagnose, and even predict the development of allergic manifestations and to treat and prevent IgE-associated allergies. Atopic dermatitis, a chronic inflammatory skin disease is almost always associated...
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ژورنال
عنوان ژورنال: Allergy
سال: 1995
ISSN: 0105-4538,1398-9995
DOI: 10.1111/j.1398-9995.1995.tb01167.x